i use 5.11 backpacks for everything in life. they're used by the military and police and last forever. i like the molle modular system to easily attach other cases or a tripod to the bag. the bags are even designed to attach attach to another bag. wrap the camera and lenses in some lens wraps and throw them in. i used the 5.11 rush 12 on a recent trip, took most of my camera gear and it held it all with no issues. the bag is about the heigh and width of a normal backpack, maybe a little deeper. it held 3 camera bodies with lenses attached, another 5 lenses, tripod, filters, and more. the rush 24 is bigger, it easily accommodates my 17" laptop
