I'm guessing you mean back button focus, where pressing a button engages autofocus, particularly useful when shooing in manual focus mode. I assigned this role to my AEL/AFL button, via Button/Dial Setting>Function (Fn) Setting in the Setup menus. The button still works as AFL, but not AEL.
My experience above was with the latest version of Acquire. I have a laptop with a version installed last year and a backup file of X-E4 settings created today with that older version could be restored with either version of Acquire.
It seems likely Fuji introduced a bug with the latest version of Acquire, at lest with regards to the X-E4. Too bad there's no way to submit a bug report.