I have used a variety of camera bags and backpacks - still haven't found one that I love - but I will give this Lowepro a serious look - maybe one size down, the 16 rather than the 22. I like to cycle with my camera, so the sling bags don't work in that situation at all. One item I have found that I really love is the Clik camera wrap - they come in multiple sizes and shapes, are entirely velcro, so close to any shape and fit. I can wrap my camera+lens in one, and toss it into any bag that I'm carrying that day, and know that it is well-protected from normal wear and tear. For long distance travel, I wrap each lens and camera body in its Clik wrap, then put it into my camera backpack - extra protection while moving around planes, trains, and autos.