Me to I had some problems to connect to PC. Make all the updates of your computer, Fujifilm X Acquire. Operating System, Chipset Drivers, maybe Bios and camera firmware.
Of course you should check for Virus first.
You can only access camera Menu when not connected to Computer. Set Connection Setting to USB Card Reader
You might also try Capture One Express for Fujifilm for Free. Check that out! It is great!