Thank you to those who provided input.
After spending more time with the X-S10, the bottom line is...it is very flexible in terms of setup! If you find yourself saying, "wouldn't it be nice if..." in terms of setting up the camera, chances are you might be able to do it, or at least get close.
This is my first Fuji, so I don't have experience with the other X-T cameras with the more traditional dials. It's been written by the expert reviewers that the X-S10 was really designed to attract other brand's DSLR users more accustomed to the PASM dial over to Fuji. As one of those relatively rare users of Pentax DSLRs, in my case I can say if that's what Fuji was aiming for, it worked.
I am enjoying the X-S10 and looking forward to spending more time with this great little camera!