No, there shouldn't be any difference, but to be honest, nearly all the camera's I've owned since 2010 have been made in China. The only Japanese camera I've owned is my X-T2. The card compartment failed, so I that got replaced, then 18 months later the main PCB board failed. I've no issues with Chinese gear at all. I think I'd actually prefer a Chinese made camera, given the choice. 20 years ago was probably a different story, but times change.
If there's one thing I know, Japanese consumers really don't like their home brand of camera's made in China, history will tell you why. From Fujifilm's point of view, business is business, if they can save money having camera's made outside of Japan they will. It would be interesting to know if Fuji dealers in Japan sell Japanese made XT-4's?