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I have a copy of Tamron’s 150 - 600mm G2 lens. It has really good image quality and is easy to use. I have heard the one you are asking about is similar. Will you be able to test it? The only drawback for me with my lens is after carrying it around for a while, it gets heavy and so on the tripod it goes. Also, it was not a FX mount lens, so I use a Fringer smart adapter, but that has never been a problem.

My first Fuji was the X-E3, it was bad to hold and I was often accidentally actuating buttons and controls. I purchased the Fuji metal handgrip for it and found it was significantly improved. Then I disabled the Q button as I was often accidentally pressing it, I also disabled the touch screen. I still own and use the camera 8 years later and it's been a great photographic tool. Maybe look into a handgrip and some adjustments to the controls before you jump ship.