I don’t think it is possible to buy one bag that will fit all your needs all the time. Which is the reason why most people end up having more than one to cover for different situations.
Yesterday I was in fact buying a small bag to cover for those moments when one or two lenses suffice and I have no need for all the extra space offered by the, admittedly, very large leather bag that I have.
One of the reasons why I don’t like now, and never liked before in my entire career as a photographer, small bags is that you can indeed fit all you need there but you will need to pile up things, often in two layers, and of course you will see that when you need lens A, it will be under lens B or C so in order you take it out you either have to put something somewhere down or you would need to grow an extra pair of hands.
I see a lot of people buying very beautiful messenger bags which really only fit a body with a lens on and one or two other lenses in one layer. Because people often tend to own more, if that’s all you have you will have to put some lenses on top of others, let alone another body with the body cap alone which you then quickly need to open and put a lens on should you ever need it, while taking all the things which are impairing access to the lens or the body.
Unfortunately, also due to a small acquired disability, my finger top dexterity has been greatly diminished in the last few years, so I might easily drop something if I try to juggle all of these things at the same time.
In other words my advise to you is to either reduce your needs to one or two bodies with two zoom lenses covering the widest possible range that you can afford, better if the two bodies each have the lenses permanently attached in order to minimize lens change, always a source of problems while on a trip.
Otherwise you need a larger bag to carry all your equipment and a smaller one to carry the equipment that you will chose for the day. Always try to picture in your mind the operative situation and how would you really work with things in the field.
You will now of course hear all sorts of brandnames ( Ona, Temba.....) from others advising you to do what they do, I am not going to do that because I am not you and you are not me.
What I can share with you is an attitude, a way of thinking,and how to work out, for yourself, what the best bag (s) is (are) for you.
Brands and types won’t help you much because they will reflect someone else’s needs and way to work with their equipment which might not be yours.